Share Email Print
cover

Proceedings Paper

Depth-resolved monitoring of analytes diffusion in ocular tissues
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Optical coherence tomography (OCT) is a noninvasive imaging technique with high in-depth resolution. We employed OCT technique for monitoring and quantification of analyte and drug diffusion in cornea and sclera of rabbit eyes in vitro. Different analytes and drugs such as metronidazole, dexamethasone, ciprofloxacin, mannitol, and glucose solution were studied and whose permeability coefficients were calculated. Drug diffusion monitoring was performed as a function of time and as a function of depth. Obtained results suggest that OCT technique might be used for analyte diffusion studies in connective and epithelial tissues.

Paper Details

Date Published: 7 February 2007
PDF: 12 pages
Proc. SPIE 6429, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI, 642918 (7 February 2007); doi: 10.1117/12.698143
Show Author Affiliations
Kirill V. Larin, Univ. of Houston (United States)
Saratov State Univ. (Russia)
Mohamad G. Ghosn, Univ. of Houston (United States)
Valery V. Tuchin, Saratov State Univ. (Russia)


Published in SPIE Proceedings Vol. 6429:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI
James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin, Editor(s)

© SPIE. Terms of Use
Back to Top