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Proceedings Paper

Direct writing of a protein micro-array: lab-on-a-chip for multipurpose sensing
Author(s): Massimiliano Rocchia; Stefano Borini; Andrea Mario Rossi; Mosè Rossi; Sabato D' Auria
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Paper Abstract

A protein microarray has been realized on a porous silicon (PS) chip by means of electron beam irradiation using a standard SEM equipped with a nanopattern generator system. Two proteins have been used to generate the array: the glucose-binding protein (GBP) and the glutamine-binding protein (GlnBP), both isolated from Escherichia coli. The proteins functionality have been tested by means of a competitive assay.

Paper Details

Date Published: 14 February 2007
PDF: 6 pages
Proc. SPIE 6444, Ultrasensitive and Single-Molecule Detection Technologies II, 644405 (14 February 2007); doi: 10.1117/12.697923
Show Author Affiliations
Massimiliano Rocchia, INRIM Istituto Nazionale di Ricerca Metrologica (Italy)
Stefano Borini, INRIM Istituto Nazionale di Ricerca Metrologica (Italy)
Andrea Mario Rossi, INRIM Istituto Nazionale di Ricerca Metrologica (Italy)
Mosè Rossi, Institute of Protein Biochemistry, CNR (Italy)
Sabato D' Auria, Institute of Protein Biochemistry, CNR (Italy)


Published in SPIE Proceedings Vol. 6444:
Ultrasensitive and Single-Molecule Detection Technologies II
Jorg Enderlein; Zygmunt K. Gryczynski, Editor(s)

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