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Proceedings Paper

Mechanisms of in vivo optical clearing of human skin at application of glycerol and lattice-like photothermal damage of stratum corneum
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Paper Abstract

Controlling of optical properties of skin is of great interest for skin diseases monitoring and phototherapy. Glycerol, as the most effective optical clearing agent, was applied in this study. Effects of osmotic properties of glycerol on optical clearing of the human skin have been investigated. Two main mechanisms of optical clearing at a creation of lattice-like pattern of localized thermal damage islets in the SC, glycerol diffusion into damaged skin and tissue dehydration, were discussed.

Paper Details

Date Published: 24 July 2006
PDF: 4 pages
Proc. SPIE 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII, 61631E (24 July 2006); doi: 10.1117/12.697340
Show Author Affiliations
Anna A. Gavrilova, Research-Educational Institute of Optics and Biophotonics, Saratov State Univ. (Russia)
Alexander B. Pravdin, Research-Educational Institute of Optics and Biophotonics, Saratov State Univ. (Russia)
Elena A. Zubkova, Research-Educational Institute of Optics and Biophotonics, Saratov State Univ. (Russia)
Valery V. Tuchin, Research-Educational Institute of Optics and Biophotonics, Saratov State Univ. (Russia)
Gregory B. Altshuler, Palomar Medical Technologies, Inc. (United States)
Ilya V. Yaroslavsky, Palomar Medical Technologies, Inc. (United States)


Published in SPIE Proceedings Vol. 6163:
Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII

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