Share Email Print
cover

Proceedings Paper

Longitudinal 3-week tracking of blood glucose concentration from thermo-optical response measurements on human skin
Author(s): Shu-jen Yeh; Stan Kantor; Charles Hanna; Eric Shain; Ronald Hohs; Omar S. Khalil
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

We designed a dual-sensor instrument for measuring optical signals from the arms of human volunteers. The instrument had two temperature-controlled localized reflectance optical probes. Each probe had one illumination fiber and four detection fibers at different source-detector distances. The two probes were maintained at 30 °C. Thirty seconds after contact with the skin one was heated and the other was cooled at the same rate. The effect of heating and cooling on the signal was measured and correlated with blood glucose concentration. The measurements were performed 3 to 5 times a day for each volunteer over the span of three weeks. The data points from the first two weeks were used to establish a calibration model for each volunteer, which was used to predict glucose values from the third week optical data. Successftil calibration was possible for two of the three volunteers.

Paper Details

Date Published: 21 July 2006
PDF: 8 pages
Proc. SPIE 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII, 61630R (21 July 2006); doi: 10.1117/12.697065
Show Author Affiliations
Shu-jen Yeh, Abbott Labs. (United States)
Stan Kantor, Abbott Labs. (United States)
Charles Hanna, Abbott Labs. (United States)
Eric Shain, Abbott Labs. (United States)
Ronald Hohs, Abbott Labs. (United States)
Omar S. Khalil, Abbott Labs. (United States)


Published in SPIE Proceedings Vol. 6163:
Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII

© SPIE. Terms of Use
Back to Top