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Proceedings Paper

Rapid NIR optical tomography at 35 frames per second by spectrally-encoded parallel light delivery
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Paper Abstract

NIR tomography has advanced considerably over the past decade. The historical developments which have led to creation of NIR tomography have largely resulted in systems which were optimized for signal accuracy and high numbers of point measurements, rather than speed of acquisition. One of the key technological designs limiting the acquisition speed is the requirement that the source light be delivered sequentially or through frequency encoding of the time signal. The approach presented here provides a method to introduce all sources and all detectors simultaneously with no moving parts and retaining the dynamic range of the detector, by separating the signals spatially prior to detection. This is achieved by spectral wavelength encoding of the sources, which allows many sources to be input into the tissue at the same time, followed by spectral-decoding of all detection channels in parallel using a spectrometer and CCD detector. A data acquisition speed of 35Hz frame rate has been achieved with this configuration. The described system features 8 sources at an overall 785nm center band and 8 detectors evenly deployed in a 27mm array designed for imaging with small animal tissues. This paper discusses the design, instrumentation of the system, and the imaging characteristics.

Paper Details

Date Published: 21 July 2006
PDF: 9 pages
Proc. SPIE 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII, 61630K (21 July 2006); doi: 10.1117/12.696968
Show Author Affiliations
Daqing Piao, Oklahoma State Univ. (United States)
Hamid Dehghani, Dartmouth College (United States)
Shudong Jiang, Dartmouth College (United States)
Subhadra Srinivasan, Dartmouth College (United States)
Brian W. Pogue, Dartmouth College (United States)


Published in SPIE Proceedings Vol. 6163:
Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII
Valery V. Tuchin, Editor(s)

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