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Proceedings Paper

Enzyme electrodes immobilized on hetero-structured metallic nanowire array for glucose sensing
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Paper Abstract

The fabrication of hetero-structured vertically aligned nanowire arrays and enzyme immobilization on their surface is presented for a glucose sensor with high sensitivity. Hetero-structured nanowires of gold and platinum are fabricated by hybrid polycarbonate membrane assembly and electrochemical deposition processes and glucose oxidase are attached on their surface by covalent immobilization. Platinum and gold hetero-structured nanoelectrodes with enzyme are evaluated to detect hydrogen peroxide produced in the enzyme reaction without the need for the artificial redox mediator, which is not viable on a homogenous gold electrode. Chronoamperometric current behavior is demonstrated with various concentrations from 0.5 mM to 28 mM. In this research, the combination of enzyme immobilization and sensing surfaces on nanowire arrays has shown superior performance with regards to the sensitivity and response time.

Paper Details

Date Published: 14 December 2006
PDF: 8 pages
Proc. SPIE 6416, Biomedical Applications of Micro- and Nanoengineering III, 641608 (14 December 2006); doi: 10.1117/12.695223
Show Author Affiliations
Hargsoon Yoon, Univ. of Arkansas (United States)
Devesh Deshpande, Univ. of Arkansas (United States)
Ritesh R. Chintakuntla, Univ. of Arkansas (United States)
Vijay K. Varadan, Univ. of Arkansas (United States)


Published in SPIE Proceedings Vol. 6416:
Biomedical Applications of Micro- and Nanoengineering III
Dan V. Nicolau, Editor(s)

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