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Proceedings Paper

Self-operated blood plasma separation using micropump in polymer-based microfluidic device
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Paper Abstract

The blood is one of the best indicators of health because blood circulates all body tissues and collects information. The COC(Cyclo Olefin Copolymer) has better various properties than PMMA(Polymethy Mechacrylate) and PC(Polycarbonate) that are widely used in biotechnology field. This paper presents a new method of plasma separation on the COC in terms of surface modification for the development of a disposable protein chip. The blood plasma separation device was composed of a whole blood inlet, microchannel with filtration region of micropillars, micropump with microheater, and a blood cell outlet. Micropump with microheater was designed by ANSYS and flow model in the microchannel was designed by CFD-ACE+ simulators. We successfully fabricated a polymer based microfluidic device for blood plasma separation by MEMS(Micro Electro Mechanical System) technology. By using this device, cell-free plasma was successfully obtained through the filtration from a drop of whole blood without external force of a syringe pump.

Paper Details

Date Published: 20 December 2006
PDF: 8 pages
Proc. SPIE 6415, Micro- and Nanotechnology: Materials, Processes, Packaging, and Systems III, 641511 (20 December 2006); doi: 10.1117/12.693475
Show Author Affiliations
Won Ick Jang, Electronics and Telecommunications Research Institute (South Korea)
Kwang Hyo Chung, Electronics and Telecommunications Research Institute (South Korea)
Hyeon Bong Pyo, Electronics and Telecommunications Research Institute (South Korea)
Seon Hee Park, Electronics and Telecommunications Research Institute (South Korea)


Published in SPIE Proceedings Vol. 6415:
Micro- and Nanotechnology: Materials, Processes, Packaging, and Systems III
Jung-Chih Chiao; Andrew S. Dzurak; Chennupati Jagadish; David Victor Thiel, Editor(s)

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