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Proceedings Paper

Hollow fiber optic probe for in vivo Raman measurement
Author(s): Takashi Katagiri; Yusuke Hattori; Yuichi Komachi; Yuji Matsuura; Hideo Tashiro; Hidetoshi Sato
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Paper Abstract

A hollow optical fiber Raman probe equipped with a ball lens is developed to study the stomach cancer. The probe generates little Raman scattering or fluorescence noise because the HOF confine light into the air core. In order to maximize the collection efficiency and the spatial resolution, material and size of the ball lens is optimized. The total diameter of the probe head is 0.64 mm. The probe is useful for measurement of layered sample by the contact mode because it has very short focal length and high depth resolution. In vivo experiments in a stomach of a living rat demonstrate the high viability of the probe for noninvasive diagnosis of the stomach cancer.

Paper Details

Date Published: 23 October 2006
PDF: 7 pages
Proc. SPIE 6380, Smart Medical and Biomedical Sensor Technology IV, 63800X (23 October 2006); doi: 10.1117/12.686634
Show Author Affiliations
Takashi Katagiri, The Institute of Physical and Chemical Research (Japan)
Yusuke Hattori, The Institute of Physical and Chemical Research (Japan)
Yuichi Komachi, Machida Endoscope Co., Ltd. (Japan)
The Institute of Physical and Chemical Research (Japan)
Yuji Matsuura, Tohoku Univ. (Japan)
Hideo Tashiro, The Institute of Physical and Chemical Research (Japan)
Hidetoshi Sato, The Institute of Physical and Chemical Research (Japan)


Published in SPIE Proceedings Vol. 6380:
Smart Medical and Biomedical Sensor Technology IV
Brian M. Cullum; J. Chance Carter, Editor(s)

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