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Proceedings Paper

Time-resolved fluorescence measurements for diffuse optical tomography using ultrafast time-correlated single photon counting
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Paper Abstract

We develop a novel approach to infer depth information about a small fluorophore-filled inclusion immersed in a scattering medium. It relies on time-resolved measurements of the time of flight distribution of emitted fluorescent photons after short pulse laser excitation. The approach uses a novel numerical constant fraction discrimination technique to assign a stable arrival time to the distribution's early photons. Our experimental results show a linear relationship between these arrival times and the position of the inclusion. This approach will serve as a useful technique in fluorescence diffuse optical tomography.

Paper Details

Date Published: 3 November 2006
PDF: 8 pages
Proc. SPIE 6372, Advanced Photon Counting Techniques, 637206 (3 November 2006); doi: 10.1117/12.685421
Show Author Affiliations
Yves Bérubé-Lauzière, Univ. de Sherbrooke (Canada)
Vincent Robichaud, Univ. de Sherbrooke (Canada)

Published in SPIE Proceedings Vol. 6372:
Advanced Photon Counting Techniques
Wolfgang Becker, Editor(s)

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