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Proceedings Paper

Intrinsic Fabry-Perot interferometer with a micrometric tip for biomedical applications
Author(s): Xingwei Wang; Juncheng Xu; Zhuang Wang; Kristie L. Cooper; Anbo Wang
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Paper Abstract

This paper presents a novel intrinsic fiber optic Fabry-Perot (FP) structure with a micrometric diameter tip. With the FP cavity inside the fiber, the change in optical path length difference (OPD) caused by the environment can be demodulated. With such a tiny protrusion, the sensor can be inserted into micron size cells for intracellular measurements. This label-free detection method is very useful in biological areas such as DNA hybridization detection. It provides a valuable tool for intracellular studies that have applications ranging from medicine to national security. In addition, the fabrication is simple including only cleaving, splicing, and etching. The signal is stable with high visibility. Last but not the least, the structure shows great promise for reduction to nanometric size. Once this goal is achieved, the sensor can be inserted into most cells with minimal invasiveness.

Paper Details

Date Published: 23 October 2006
PDF: 5 pages
Proc. SPIE 6380, Smart Medical and Biomedical Sensor Technology IV, 638005 (23 October 2006); doi: 10.1117/12.685088
Show Author Affiliations
Xingwei Wang, Virginia Polytechnic Institute and State Univ. (United States)
Juncheng Xu, Virginia Polytechnic Institute and State Univ. (United States)
Zhuang Wang, Virginia Polytechnic Institute and State Univ. (United States)
Kristie L. Cooper, Virginia Polytechnic Institute and State Univ. (United States)
Anbo Wang, Virginia Polytechnic Institute and State Univ. (United States)


Published in SPIE Proceedings Vol. 6380:
Smart Medical and Biomedical Sensor Technology IV
Brian M. Cullum; J. Chance Carter, Editor(s)

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