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Proceedings Paper

Photobiomodulation in laser surgery
Author(s): Timon Cheng-Yi Liu; Dong-Liang Rong; Jin Huang; Xiao-Yuan Deng; Song-Hao Liu
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Paper Abstract

Laser surgery provides good exposure with clear operating fields and satisfactory preliminary functional results. In contrast to conventional excision, it was found that matrix metalloproteinases and the tissue inhibitors of metalloproteinases -1 mRNA expression is higher, myofibroblasts appeared and disappeared slower in laser excision wounds. It has been suggested that the better anatomical and functional results achieved following laser cordectomy may be explained by the fact that such procedures result in better, more rapid healing processes to recover vocal cord for early glottic tumors and better. In this paper, the role of photobiomodulation in laser surgery will be discussed by the cultured monolayer normal human skin fibroblast model of the photobiomodulation of marginal irradiation of high intensity laser beam, the photobiomodulation related to the irradiated tissue, the biological information model of photobiomodulation and the animal models of laser surgery. Although high intensity laser beam is so intense that it destroys the irradiated cells or tissue, its marginal irradiation intensity is so low that there is photobiomodulation on non-damage cells to modulate the regeneration of partly damaged tissue so that the surgery of laser of different parameters results in different post-surgical recovery. It was concluded that photobiomodulation might play an important role in the long-term effects of laser surgery, which might be used to design laser surgery.

Paper Details

Date Published: 2 February 2006
PDF: 5 pages
Proc. SPIE 6026, ICO20: Biomedical Optics, 60260C (2 February 2006); doi: 10.1117/12.667106
Show Author Affiliations
Timon Cheng-Yi Liu, South China Normal Univ. (China)
Dong-Liang Rong, South China Normal Univ. (China)
Jin Huang, South China Normal Univ. (China)
Xiao-Yuan Deng, South China Normal Univ. (China)
Song-Hao Liu, South China Normal Univ. (China)


Published in SPIE Proceedings Vol. 6026:
ICO20: Biomedical Optics
Gert von Bally; Qingming Luo, Editor(s)

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