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Proceedings Paper

Laser light propagation in adipose tissue and laser effects on adipose cell membranes
Author(s): Efraín Solarte; Aldo Rebolledo; Oscar Gutierrez; William Criollo; Rodrigo Neira; José Arroyave; Hugo Ramírez
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Paper Abstract

Recently Neira et al. have presented a new liposuction technique that demonstrated the movement of fat from inside to outside of the cell, using a low-level laser device during a liposuction procedure with Ultrawet solution. The clinical observations, allowed this new surgical development, started a set of physical, histological and pharmacological studies aimed to determine the mechanisms involved in the observed fat mobilization concomitant to external laser application in liposuction procedures. Scanning and Transmission Electron Microscopy, studies show that the cellular arrangement of normal adipose tissue changes when laser light from a diode laser: 10 mW, 635 nm is applied. Laser exposures longer than 6 minutes cause the total destruction of the adipocyte panicles. Detailed observation of the adipose cells show that by short irradiation times (less than four minutes) the cell membrane exhibits dark zones, that collapse by longer laser exposures. Optical measurements show that effective penetration length depends on the laser intensity. Moreover, the light scattering is enhanced by diffraction and subsequent interference effects, and the tumescent solution produces a clearing of the tissue optical medium. Finally, isolate adipose cell observation show that fat release from adipocytes is a concomitant effect between the tumescent solution (adrenaline) and laser light, revealing a synergism which conduces to the aperture, and maybe the disruption, of the cell membrane. All these studies were consistent with a laser induced cellular process, which causes fat release from inside the adipocytes into the intercellular space, besides a strong modification of the cellular membranes.

Paper Details

Date Published: 2 February 2006
PDF: 9 pages
Proc. SPIE 6026, ICO20: Biomedical Optics, 602605 (2 February 2006); doi: 10.1117/12.667088
Show Author Affiliations
Efraín Solarte, Univ. del Valle (Colombia)
Aldo Rebolledo, Univ. del Valle (Colombia)
Oscar Gutierrez, Univ. del Valle (Colombia)
William Criollo, Univ. del Valle (Colombia)
Rodrigo Neira, Ctr. Médico Imbanaco (Colombia)
José Arroyave, Ctr. Internacional de Agricultura Tropical (Colombia)
Hugo Ramírez, Univ. Libre (Colombia)


Published in SPIE Proceedings Vol. 6026:
ICO20: Biomedical Optics
Gert von Bally; Qingming Luo, Editor(s)

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