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Proceedings Paper

Effect of low-level laser (LLL) on cochlear and vestibular inner ear including tinnitus
Author(s): Chung-Ku Rhee; Eun-Seok Lim; Young-Saeng Kim; Yong-Won Chung; Jae-Yun Jung; Phil-Sang Chung
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Paper Abstract

Objectives: 1. To investigate preventive effect of LLL on gentamicin-induced vestibular ototoxicity. 2. To evaluate the effectiveness of lower level laser (LLL) in the treatment of tinnitus. Methods: 1. Twenty guinea pigs were divided into control and laser groups. Vestibular ototoxicity was induced by intratympanic injection of gentamicin into left ear. LLL was irradiated into left ear canal of animals in laser group. Vestibular function of the animals was evaluated with vertical and off-vertical axis rotation testing. 2. Forty patients with tinnitus were treated with ginkgo biloba orally and randomly divided into control and laser groups. The 20 patients of laser group received 80.4 J/cm2 of 830 nm laser, 3 times per week for 4 weeks, via transmeatal irradiation. Tinnitus was evaluated by visual analogue scale (VAS) and tinnitus handicap inventory (THI). Results: 1. Preventive effect of LLL to gentamicin induced vestibular ototoxicity was demonstrated by preventing reduction of gain in slow harmonic acceleration test and modulation in the off-vertical axis rotation test. 2. Eleven of 20 laser group patients have shown significant improvement in VAS and THI compared to those of the control group. Conclusions: 1. LLL therapy may have preventive effect to vestibular ototoxicity. 2. LLL therapy in combination with ginkgo biloba seems to be worth trying on patients with tinnitus.

Paper Details

Date Published: 22 February 2006
PDF: 12 pages
Proc. SPIE 6078, Photonic Therapeutics and Diagnostics II, 60781K (22 February 2006); doi: 10.1117/12.659654
Show Author Affiliations
Chung-Ku Rhee, Dankook Univ. (South Korea)
Eun-Seok Lim, Dankook Univ. (South Korea)
Young-Saeng Kim, Dankook Univ. (South Korea)
Yong-Won Chung, Dankook Univ. (South Korea)
Jae-Yun Jung, Dankook Univ. (South Korea)
Phil-Sang Chung, Dankook Univ. (South Korea)

Published in SPIE Proceedings Vol. 6078:
Photonic Therapeutics and Diagnostics II
Kenton W. Gregory; Nikiforos Kollias; Reza S. Malek; Michael D. Lucroy; Henry Hirschberg; Brian Jet-Fei Wong; Eugene A. Trowers; Werner T.W. de Riese; Justus F. R. Ilgner; Steen J. Madsen; Lloyd P. Tate; Haishan Zeng; Guillermo J. Tearney; Bernard Choi, Editor(s)

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