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Proceedings Paper

Bladder cancer diagnosis with fluorescence-image-guided optical coherence tomography
Author(s): Gregg Douglas Sucha; Gennady Imeshev; Michelle Lynn Stock
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Paper Abstract

A fluorescence-image-guided OCT (FIG-OCT) system is described, and its ability to enhance the sensitivity and specificity is examined in an animal bladder cancer model. Total 97 specimens were examined by fluorescence imaging, OCT and histological microscopy. The sensitivity and specificity of FIG-OCT is 100% and 93% respectively, compared to 79% and 53% for fluorescence imaging, while the OCT examination time has been dramatically decreased by 3~4 times. In combination of endoscopic OCT, FIG-OCT is a promising technique for effective early bladder cancer diagnosis.

Paper Details

Date Published:
Proc. SPIE 6102, Fiber Lasers III: Technology, Systems, and Applications, 61020J; doi: 10.1117/12.659626
Show Author Affiliations
Gregg Douglas Sucha, IMRA America, Inc. (United States)
Gennady Imeshev, IMRA America, Inc. (United States)
Michelle Lynn Stock, IMRA America, Inc. (United States)

Published in SPIE Proceedings Vol. 6102:
Fiber Lasers III: Technology, Systems, and Applications
Andrew J. W. Brown; Johan Nilsson; Donald J. Harter; Andreas Tünnermann, Editor(s)

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