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Proceedings Paper

Dynamic laser speckles as applied to the study of laser-mediated structural changes of the collagenous biotissues
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Paper Abstract

The potential for monitoring of the laser-mediated thermal modification of tissue by means dynamic laser speckles methods is examined. The specific case of delivering of speckle-modulated light backscattered by cartilage with the use of a fiber-optic bundle probe is considered. The proposed technique is experimentally compared with the conventional laser speckle contrast analysis. Both techniques similarly display the basic features of laser-mediated alterations in tissue but the bundle-based technique provides the monitoring of tissue modification with more details and more pronounced correlation between the speckle contrast and the tissue temperature. The possibility of evaluation of the fundamental physical-chemical parameters of tissue modification (in particular, the activation energy) from the temperature-dependent dynamics of the speckle contrast is demonstrated.

Paper Details

Date Published: 3 March 2006
PDF: 8 pages
Proc. SPIE 6085, Complex Dynamics and Fluctuations in Biomedical Photonics III, 608509 (3 March 2006); doi: 10.1117/12.659326
Show Author Affiliations
Liana V. Kuznetsova, Saratov State Univ. (Russia)
Dmitry A. Zimnyakov, Saratov State Univ. (Russia)
Alexander P. Sviridov, Institute of Laser and Information Technologies (Russia)
Stepan A. Baranov, Institute of Laser and Information Technologies (Russia)
Natali Y. Ignatieva, Institute of Laser and Information Technologies (Russia)


Published in SPIE Proceedings Vol. 6085:
Complex Dynamics and Fluctuations in Biomedical Photonics III
Valery V. Tuchin, Editor(s)

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