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Proceedings Paper

Packaged Au-PPy valves for drug delivery systems
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Paper Abstract

The most common methods for the drug delivery are swallowing pills or receiving injections. However, formulations that control the rate and period of medicine (i.e., time-release medications) are still problematic. The proposed implantable devices which include batteries, sensors, telemetry, valves, and drug storage reservoirs provide an alternative method for the responsive drug delivery system [1]. Using this device, drug concentration can be precisely controlled which enhances drug efficiency and decreases the side effects. In order to achieve responsive drug delivery, a reliable release valve has to be developed. Biocompatibility, low energy consumption, and minimized leakage are the main requirements for such release method. A bilayer structure composed of Au/PPy film is fabricated as a flap to control the release valve. Optimized potentiostatic control to synthesize polypyrrole (PPy) is presented. The release of miniaturize valve is tested and showed in this paper. A novel idea to simultaneously fabricate the device reservoirs as well as protective packaging is proposed in this paper. The solution of PDMS permeability problem is also mentioned in this article.

Paper Details

Date Published: 22 March 2006
PDF: 6 pages
Proc. SPIE 6168, Smart Structures and Materials 2006: Electroactive Polymer Actuators and Devices (EAPAD), 61681E (22 March 2006); doi: 10.1117/12.658742
Show Author Affiliations
Han-Kuan Anthony Tsai, Univ. of California/Irvine (United States)
Kuo-Sheng Ma, Univ. of California/Irvine (United States)
Jim Zoval, Univ. of California/Irvine (United States)
Lawrence Kulinsky, Univ. of California/Irvine (United States)
Marc J. Madou, Univ. of California/Irvine (United States)

Published in SPIE Proceedings Vol. 6168:
Smart Structures and Materials 2006: Electroactive Polymer Actuators and Devices (EAPAD)
Yoseph Bar-Cohen, Editor(s)

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