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Proceedings Paper

Characterization of malaria infected blood cells by scanning confocal laser and acoustic vector contrast microscopy
Author(s): E. T. Ahmed Mohamed; S. Schubert; T. W. Gilberger; A. Kamanyi; R. Wannemacher; W. Grill
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Paper Abstract

Acoustic and optical multiple contrast microscopy has been employed in order to explore characterizable parameters of red blood cells, including cells infected by the parasite Plasmodium falciparum, in order to investigate cellular modifications caused by the infection and to identify possible detection schemes for disease monitoring. Imaging schemes were based on fluorescence, optical transmission, optical reflection, and amplitude and phase of ultrasound reflected from the cells. Contrast variations observed in acoustic microscopy, but not in optical microscopy, were tentatively ascribed to changes caused by the infection.

Paper Details

Date Published: 15 March 2006
PDF: 6 pages
Proc. SPIE 6177, Health Monitoring and Smart Nondestructive Evaluation of Structural and Biological Systems V, 617716 (15 March 2006); doi: 10.1117/12.657892
Show Author Affiliations
E. T. Ahmed Mohamed, Univ. of Leipzig (Germany)
S. Schubert, Univ. of Leipzig (Germany)
T. W. Gilberger, Bernhard Nocht Institute for Tropical Medicine (Germany)
A. Kamanyi, Univ. of Leipzig (Germany)
R. Wannemacher, Univ. of Leipzig (Germany)
W. Grill, Univ. of Leipzig (Germany)


Published in SPIE Proceedings Vol. 6177:
Health Monitoring and Smart Nondestructive Evaluation of Structural and Biological Systems V
Tribikram Kundu, Editor(s)

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