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Proceedings Paper

Unsupervised definition of the tibia-femoral joint regions of the human knee and its applications to cartilage analysis
Author(s): José Gerardo Tamez-Peña; Monica Barbu-McInnis; Saara Totterman
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Paper Abstract

Abnormal MR findings including cartilage defects, cartilage denuded areas, osteophytes, and bone marrow edema (BME) are used in staging and evaluating the degree of osteoarthritis (OA) in the knee. The locations of the abnormal findings have been correlated to the degree of pain and stiffness of the joint in the same location. The definition of the anatomic region in MR images is not always an objective task, due to the lack of clear anatomical features. This uncertainty causes variance in the location of the abnormality between readers and time points. Therefore, it is important to have a reproducible system to define the anatomic regions. This works present a computerized approach to define the different anatomic knee regions. The approach is based on an algorithm that uses unique features of the femur and its spatial relation in the extended knee. The femur features are found from three dimensional segmentation maps of the knee. From the segmentation maps, the algorithm automatically divides the femur cartilage into five anatomic regions: trochlea, medial weight bearing area, lateral weight bearing area, posterior medial femoral condyle, and posterior lateral femoral condyle. Furthermore, the algorithm automatically labels the medial and lateral tibia cartilage. The unsupervised definition of the knee regions allows a reproducible way to evaluate regional OA changes. This works will present the application of this automated algorithm for the regional analysis of the cartilage tissue.

Paper Details

Date Published: 15 March 2006
PDF: 11 pages
Proc. SPIE 6144, Medical Imaging 2006: Image Processing, 61444K (15 March 2006); doi: 10.1117/12.654164
Show Author Affiliations
José Gerardo Tamez-Peña, VirtualScopics, Inc (United States)
Monica Barbu-McInnis, VirtualScopics, Inc (United States)
Saara Totterman, VirtualScopics, Inc (United States)


Published in SPIE Proceedings Vol. 6144:
Medical Imaging 2006: Image Processing
Joseph M. Reinhardt; Josien P. W. Pluim, Editor(s)

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