Share Email Print
cover

Proceedings Paper

Subtraction computed tomographic angiography: use of pre-contrast images for calcification removal
Author(s): Peter J. Yim; John L. Nosher
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Arterial stenoses may be obscured by calcified atherosclerotic plaque in computed tomographic angiography (CTA). A technique of subtraction computed tomographic angiography (sCTA) for calcification removal is proposed and evaluated in a preliminary manner. In the proposed sCTA method, the examination includes a pre-contrast computed tomogram (pcCT) and a CTA. The pcCT is performed using the CTA scan protocol. Subtraction of the registered pcCT from the CTA is performed after calcifications in the pcCT are registered to the CTA using a piecewise-rigid transformation model. The registration is based on a maximum-cancellation cost-function. Points at the boundary of the artery in the CTA are given a greater weight in the cost function than those towards the center of the artery. sCTA was evaluated using a calcified-artery phantom whose dimensions approximate those of the superficial femoral artery. The phantom represented both calcified plaque surrounding stenotic segments of the artery. pcCT and CTA's were obtained on a 4-multidetector-row CT system with 1.25-mm slice thickness and 0.7-mm in-plane resolution. The phantom was slightly displaced between the pcCT and the CTA. sCTA closely resembled a gold-standard image of the phantom that was obtained with the calcification material removed. The sCTA accurately demonstrated the degree of stenosis and artifacts in the sCTA were minimal. This study demonstrates in a preliminary manner that sCTA is feasible.

Paper Details

Date Published: 13 March 2006
PDF: 7 pages
Proc. SPIE 6143, Medical Imaging 2006: Physiology, Function, and Structure from Medical Images, 61432L (13 March 2006); doi: 10.1117/12.654088
Show Author Affiliations
Peter J. Yim, Univ. of Medicine and Dentristy of New Jersey, Robert Wood Johnson Medical School (United States)
John L. Nosher, Univ. of Medicine and Dentristy of New Jersey, Robert Wood Johnson Medical School (United States)


Published in SPIE Proceedings Vol. 6143:
Medical Imaging 2006: Physiology, Function, and Structure from Medical Images
Armando Manduca; Amir A. Amini, Editor(s)

© SPIE. Terms of Use
Back to Top