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Proceedings Paper

Development and implementation of a user friendly and automated environment for the creation of databases of digital mammograms with simulated microcalcifications
Author(s): Federica Zanca; Jurgen Jacobs; Paula Pöyry; Chantal Van Ongeval; Ann-Catherine Carton; Tom Deprez; Guy Marchal; Hilde Bosmans
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Paper Abstract

A database of raw composite mammograms containing simulated microcalcifications was generated. Databases can be used for technology assessment, quality assurance and comparison of different processing algorithms or different visualization modalities in digital mammography. Clinical mammograms were selected and fully documented for this scope. Microcalcifications were simulated in mammography images following a methodology developed and validated in an earlier work of our group. To create microcalcification templates, specimen containing lesions with different morphology types were acquired. From a basic set of (ideal) microcalcification templates, a set of specific templates for the systems under study was generated. The necessary input to do so is the system MTF and attenuation values of aluminum sheets with different thickness. In order to make the whole process less time consuming and applicable on a large scale, dedicated software tools for the creation of composite images have been developed. Automatic analysis of scores from observer performance study, in terms of microcalcification detectability on the composite images, is also implemented. We report on the functionalities foreseen in these new software tools. Simulated microcalcifications were successfully created and inserted in raw images of the Siemens Novation DR, the AGFA DM1000 and the AGFA CR MM2.0.

Paper Details

Date Published: 17 March 2006
PDF: 8 pages
Proc. SPIE 6146, Medical Imaging 2006: Image Perception, Observer Performance, and Technology Assessment, 614615 (17 March 2006); doi: 10.1117/12.653135
Show Author Affiliations
Federica Zanca, Leuven Univ. Ctr. of Medical Physics in Radiology (Belgium)
Jurgen Jacobs, Leuven Univ. Ctr. of Medical Physics in Radiology (Belgium)
Paula Pöyry, STUK Radiation and Nuclear Safety Authority (Finland)
Chantal Van Ongeval, Leuven Univ. Ctr. of Medical Physics in Radiology (Belgium)
Ann-Catherine Carton, Hospital of the Univ. of Pennsylvania (United States)
Tom Deprez, Leuven Univ. Ctr. of Medical Physics in Radiology (Belgium)
Guy Marchal, Leuven Univ. Ctr. of Medical Physics in Radiology (Belgium)
Hilde Bosmans, Leuven Univ. Ctr. of Medical Physics in Radiology (Belgium)


Published in SPIE Proceedings Vol. 6146:
Medical Imaging 2006: Image Perception, Observer Performance, and Technology Assessment
Yulei Jiang; Miguel P. Eckstein, Editor(s)

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