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Proceedings Paper

Development of a high frame rate ultrasonic system for cardiac imaging in small animals
Author(s): Lei Sun; Jonathan M. Cannata; Jeffrey A. Johnson; Jesse T. Yen; Ching Feng; K. Kirk Shung
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Paper Abstract

Ultrasound imaging is a well established technology for echocardiography on humans. For cardiac imaging in small animals whose hearts beat at a rate higher than 300 beats per minute, the spatial and temporal resolution of current clinical ultrasonic scanners are far from ideal and simply inadequate for such applications. In this research, a real-time high frequency ultrasound imaging system was developed with a frame rate higher than 80 frames per second (fps) for cardiac applications in small animals. The device has a mechanical sector scanner using magnetic drive mechanism to reduce moving parts and ensure longevity. A very lightweight (< 0.28 g) single element transducer was specially designed and constructed for this research to achieve a frame rate of at least 80 fps. The 30-50 MHz transducers swept through an arc at the end of a pendulum for imaging the heart of small animals. The imaging electronics consisted of a low noise pulser/receiver, a high-speed data acquisition board, and digital signal processing algorithms. In vivo results on mouse embryos showed that real time ultrasound imaging at frame rate exceeding 80 fps could demonstrate detailed depiction of cardiac function with a spatial resolution of around 50 microns, which allows researchers to fully examine and monitor small animal cardiac functions.

Paper Details

Date Published: 16 March 2006
PDF: 7 pages
Proc. SPIE 6147, Medical Imaging 2006: Ultrasonic Imaging and Signal Processing, 61470R (16 March 2006); doi: 10.1117/12.652280
Show Author Affiliations
Lei Sun, Univ. of Southern California (United States)
Jonathan M. Cannata, Univ. of Southern California (United States)
Jeffrey A. Johnson, Capistrano Labs., Inc. (United States)
Jesse T. Yen, Univ. of Southern California (United States)
Ching Feng, Capistrano Labs., Inc. (United States)
K. Kirk Shung, Univ. of Southern California (United States)


Published in SPIE Proceedings Vol. 6147:
Medical Imaging 2006: Ultrasonic Imaging and Signal Processing
Stanislav Emelianov; William F. Walker, Editor(s)

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