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Proceedings Paper

Dedicated registration for DCE MRI mammography
Author(s): Steffen Renisch; Thomas Bülow; Ingwer C. Carlsen; Astrid Franz
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Paper Abstract

Dynamic contrast enhanced (DCE) MRI mammography is currently receiving much interest in clinical research. It bears the potential to discriminate between benign and malignant lesions by analysis of the contrast uptake of the lesion. However, a registration of the individual images of a contrast-uptake series is crucial in order to avoid motion artefacts in the uptake curves, which could affect the diagnosis. It is on the other hand well known from the registration literature that a registration that uses a standard similarity measure (e.g. mean sum of squared differences, cross-correlation) may cause artefacts if contrast agent is taken up between the images to be registered. Thus we propose a registration on the basis of an application-specific similarity measure that explicitly uses features of the contrast uptake. We report initial results using this registration method.

Paper Details

Date Published: 10 March 2006
PDF: 12 pages
Proc. SPIE 6144, Medical Imaging 2006: Image Processing, 61442C (10 March 2006); doi: 10.1117/12.651597
Show Author Affiliations
Steffen Renisch, Philips Research Labs. (Germany)
Thomas Bülow, Philips Research Labs. (Germany)
Ingwer C. Carlsen, Philips Research Labs. (Germany)
Astrid Franz, Philips Research Labs. (Germany)


Published in SPIE Proceedings Vol. 6144:
Medical Imaging 2006: Image Processing
Joseph M. Reinhardt; Josien P. W. Pluim, Editor(s)

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