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Proceedings Paper

Statistical parametric mapping for in vivo MRI assessment of morphological changes in rat articular cartilage
Author(s): Ping Chiao; Zhiyong Xie; Shantanu Dhamija; Serguei Liachenko; Michael Gieseg
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Paper Abstract

This paper explores the use of statistical parametric mapping, which has been widely used in brain imaging applications, in the assessment of morphological changes in rat articular cartilage during OA. This approach can not only detect but also localize changes, effectively zooming in statistically more informative areas and therefore maximizing the sensitivity. The analysis of in-vivo MR images of rat articular cartilage demonstrates that the new approach is at least as sensitive as the cartilage volume analysis.

Paper Details

Date Published: 13 March 2006
PDF: 7 pages
Proc. SPIE 6143, Medical Imaging 2006: Physiology, Function, and Structure from Medical Images, 614326 (13 March 2006); doi: 10.1117/12.650625
Show Author Affiliations
Ping Chiao, Pfizer, Inc. (United States)
Zhiyong Xie, Pfizer, Inc. (United States)
Shantanu Dhamija, Pfizer, Inc. (United States)
Serguei Liachenko, Pfizer, Inc. (United States)
Michael Gieseg, Pfizer, Inc. (United States)


Published in SPIE Proceedings Vol. 6143:
Medical Imaging 2006: Physiology, Function, and Structure from Medical Images
Armando Manduca; Amir A. Amini, Editor(s)

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