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Proceedings Paper

Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors
Author(s): Sandra Miskoski; Luciana Giordano; Maria H. Etchehon; Guillermo Menendez; Keith A. Lidke; Guy M. Hagen; Thomas M. Jovin; Elizabeth A. Jares-Erijman
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Paper Abstract

Multifunctional nanoparticles, quantum dots (QDs) are being developed as uniquely sensitive tools for elucidating the (bio)chemical and (bio)physical molecular mechanisms underlying functional states, i.e. the molecular physiology, of biological cells and organisms. Here we present a group of strategies and examples for (i) controlling the spectroscopic properties of QDs via Fluorescence Resonance Energy Transfer (FRET); (ii) determining the emission spectra of individual QDs in a population with an imaging spectrograph (ASI SpectraCube); and (iii) employing such liganded QDs as nano-probes in cellular studies of signal transduction.

Paper Details

Date Published: 27 March 2006
PDF: 8 pages
Proc. SPIE 6096, Colloidal Quantum Dots for Biomedical Applications, 60960X (27 March 2006); doi: 10.1117/12.649835
Show Author Affiliations
Sandra Miskoski, Univ. de Buenos Aires (Argentina)
Luciana Giordano, Univ. de Buenos Aires (Argentina)
Maria H. Etchehon, Univ. de Buenos Aires (Argentina)
Guillermo Menendez, Univ. de Buenos Aires (Argentina)
Keith A. Lidke, Max Planck Institute for Biophysical Chemistry (Germany)
Sandia National Labs. (United States)
Guy M. Hagen, Max Planck Institute for Biophysical Chemistry (Germany)
Thomas M. Jovin, Max Planck Institute for Biophysical Chemistry (Germany)
Elizabeth A. Jares-Erijman, Univ. de Buenos Aires (Argentina)

Published in SPIE Proceedings Vol. 6096:
Colloidal Quantum Dots for Biomedical Applications
Marek Osinski; Kenji Yamamoto; Thomas M. Jovin M.D., Editor(s)

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