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Proceedings Paper

Bladder cancer diagnosis with fluorescence-image-guided optical coherence tomography
Author(s): Z. G. Wang; D. B. Durand; Howard L. Adler; Y. T. Pan
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Paper Abstract

A fluorescence-image-guided OCT (FIG-OCT) system is described, and its ability to enhance the sensitivity and specificity is examined in an animal bladder cancer model. Total 97 specimens were examined by fluorescence imaging, OCT and histological microscopy. The sensitivity and specificity of FIG-OCT is 100% and 93% respectively, compared to 79% and 53% for fluorescence imaging, while the OCT examination time has been dramatically decreased by 3~4 times. In combination of endoscopic OCT, FIG-OCT is a promising technique for effective early bladder cancer diagnosis.

Paper Details

Date Published: 20 February 2006
PDF: 7 pages
Proc. SPIE 6079, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X, 60790L (20 February 2006); doi: 10.1117/12.649117
Show Author Affiliations
Z. G. Wang, SUNY at Stony Brook (United States)
D. B. Durand, SUNY at Stony Brook (United States)
Howard L. Adler, SUNY at Stony Brook (United States)
Y. T. Pan, SUNY at Stony Brook (United States)


Published in SPIE Proceedings Vol. 6079:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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