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Proceedings Paper

Directional polarization sensitivity of articular cartilage by optical coherence tomography
Author(s): Tuqiang Xie; Shouguang Guo; Jun Zhang; Zhongping Chen; George M. Peavy
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Paper Abstract

In this paper, the polarization sensitivity of articular cartilage was investigated by using polarization sensitivity optical coherence tomography (PS-OCT) obtained by varying the angel of incident illumination. Experimental results show that when the incident light is perpendicular to the tissue surface, normal articular cartilage demonstrates little polarization sensitivity. Significant variations in birefringence of articular cartilage observed when the angle of incident light was adjusted between 0° and 90° relative to the tissue surface. Directional polarization sensitivity of articular cartilage as obtained by PS-OCT imaging using variations in the angle of incident illumination can be used to access the orientation and organization of the collagen matrix of these tissues. The polarization sensitivity and the birefringence images obtained can be explained by the angle of illumination relative to the unique microstructure and orientation of the collagen fibrils and fibers of articular cartilage.

Paper Details

Date Published: 20 February 2006
PDF: 8 pages
Proc. SPIE 6079, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X, 60792E (20 February 2006); doi: 10.1117/12.649112
Show Author Affiliations
Tuqiang Xie, Beckman Laser Institute (United States)
Shouguang Guo, Beckman Laser Institute (United States)
Jun Zhang, Beckman Laser Institute (United States)
Zhongping Chen, Beckman Laser Institute (United States)
George M. Peavy, Beckman Laser Institute (United States)


Published in SPIE Proceedings Vol. 6079:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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