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Proceedings Paper

Multiphoton nanosurgery in cells and tissues
Author(s): Iris Riemann; Frank Stracke; Daniel Sauer; Sven Martin; Karsten König
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Paper Abstract

Near infrared (NIR) femtosecond laser microscopes enable the user to perform highly precise nanosurgery. Tissue components, cells and single organelles of cells inside tumor-sphaeroids and tissues can be precisely manipulated and optically knocked out without collateral damage. In addition, the monitoring effects of nanosurgery in situ using two photon excitation of auto fluorescence of endogenous fluorophores can be performed quite easily with a sub-cellular resolution. This method may become a useful instrument for nano manipulation and nano-surgery in several fields of life sciences.

Paper Details

Date Published: 23 February 2006
PDF: 7 pages
Proc. SPIE 6089, Multiphoton Microscopy in the Biomedical Sciences VI, 608918 (23 February 2006); doi: 10.1117/12.646096
Show Author Affiliations
Iris Riemann, Fraunhofer Institute of Biomedical Technology (Germany)
Frank Stracke, Fraunhofer Institute of Biomedical Technology (Germany)
Daniel Sauer, Fraunhofer Institute of Biomedical Technology (Germany)
Sven Martin, JenLab GmbH (Germany)
Karsten König, Fraunhofer Institute of Biomedical Technology (Germany)


Published in SPIE Proceedings Vol. 6089:
Multiphoton Microscopy in the Biomedical Sciences VI
Ammasi Periasamy; Peter T. C. So, Editor(s)

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