Share Email Print
cover

Proceedings Paper

A noninvasive optical probe for breast cancer: diagnostic use of acoustically induced blood stasis
Author(s): B. A. Winey; V. Misic; B. Fenton; L. Liao; K. Parker; Y. Yu
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Ultrasound-induced blood stasis was demonstrated thirty years ago. Most of the literature has been focused on methods employed to prevent stasis from occurring during ultrasound imaging. The current work discusses some of the theory behind this phenomenon. It also demonstrates ultrasound-induced blood stasis in murine tumor and muscle tissue, observed through noninvasive measurements of optical spectroscopy, and discusses possible diagnostic uses. We demonstrate that, using optical spectroscopy, effects of ultrasound can be used to noninvasively differentiate tumor from muscle tissue in mice, and that we can quantitatively differentiate tumor from muscle with maximum specificity 0.83, maximum sensitivity 0.79, and area under ROC curve 0.90, using a simple algorithm.

Paper Details

Date Published: 6 March 2006
PDF: 8 pages
Proc. SPIE 6086, Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 60860N (6 March 2006); doi: 10.1117/12.646091
Show Author Affiliations
B. A. Winey, Univ. of Rochester (United States)
V. Misic, Univ. of Rochester Medical Ctr. (United States)
B. Fenton, Univ. of Rochester Medical Ctr. (United States)
L. Liao, Univ. of Rochester Medical Ctr. (United States)
K. Parker, Univ. of Rochester (United States)
Y. Yu, Univ. of Rochester Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 6086:
Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

© SPIE. Terms of Use
Back to Top