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Proceedings Paper

A novel laser angioplasty guided hollow fiber using mid-infrared laser
Author(s): Sachiko Yoshihashi-Suzuki; Shinya Yamada; Izuru Sato; Kunio Awazu
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Paper Abstract

We have proposed selective removal of cholesterol ester by infrared laser of wavelength with 5.75 μm irradiation; the wavelength of 5.75 μm correspond with the ester bond C=O stretching vibration. The flexible laser guiding line and a compact light source are required for our proposal. We used a compact mid-infrared tunable laser by difference frequency generation; DFG laser was developed for substitute light source of free electron laser. In the present work, first, we have developed hollow optical fiber with a diamond lens-tip to deliver DFG laser in the blood vessel and evaluated the transmission of DFG laser from 5.5 μm to 7.5 μm. The transmission of 5.75 μm is about 65%, the DFG beam was focused on the tip of fiber by diamond lens-tip. Secondly, we performed the selective removal experiment of cholesterol ester using the hollow optical fiber with diamond lens-tip and DFG laser. The sample used a two layer model, cholesterol oleate and gelatin. The cholesterol oleate was decomposed by 5.75 μm DFG irradiation with 3.8 W/cm2.

Paper Details

Date Published: 15 February 2006
PDF: 7 pages
Proc. SPIE 6083, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VI, 60830I (15 February 2006); doi: 10.1117/12.645895
Show Author Affiliations
Sachiko Yoshihashi-Suzuki, Osaka Univ. (Japan)
Shinya Yamada, Osaka Univ. (Japan)
Izuru Sato, Osaka Univ. (Japan)
Kunio Awazu, Osaka Univ. (Japan)


Published in SPIE Proceedings Vol. 6083:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VI
Israel Gannot, Editor(s)

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