Share Email Print

Proceedings Paper

A novel laser angioplasty guided hollow fiber using mid-infrared laser
Author(s): Sachiko Yoshihashi-Suzuki; Shinya Yamada; Izuru Sato; Kunio Awazu
Format Member Price Non-Member Price
PDF $17.00 $21.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We have proposed selective removal of cholesterol ester by infrared laser of wavelength with 5.75 μm irradiation; the wavelength of 5.75 μm correspond with the ester bond C=O stretching vibration. The flexible laser guiding line and a compact light source are required for our proposal. We used a compact mid-infrared tunable laser by difference frequency generation; DFG laser was developed for substitute light source of free electron laser. In the present work, first, we have developed hollow optical fiber with a diamond lens-tip to deliver DFG laser in the blood vessel and evaluated the transmission of DFG laser from 5.5 μm to 7.5 μm. The transmission of 5.75 μm is about 65%, the DFG beam was focused on the tip of fiber by diamond lens-tip. Secondly, we performed the selective removal experiment of cholesterol ester using the hollow optical fiber with diamond lens-tip and DFG laser. The sample used a two layer model, cholesterol oleate and gelatin. The cholesterol oleate was decomposed by 5.75 μm DFG irradiation with 3.8 W/cm2.

Paper Details

Date Published: 15 February 2006
PDF: 7 pages
Proc. SPIE 6083, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VI, 60830I (15 February 2006); doi: 10.1117/12.645895
Show Author Affiliations
Sachiko Yoshihashi-Suzuki, Osaka Univ. (Japan)
Shinya Yamada, Osaka Univ. (Japan)
Izuru Sato, Osaka Univ. (Japan)
Kunio Awazu, Osaka Univ. (Japan)

Published in SPIE Proceedings Vol. 6083:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VI
Israel Gannot, Editor(s)

© SPIE. Terms of Use
Back to Top