Share Email Print
cover

Proceedings Paper

Visible lesion thresholds and model predictions for Q-switched 1318-nm and 1540-nm laser exposures to porcine skin
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Skin damage thresholds were measured and compared with theoretical predictions using a skin thermal model for near-IR laser pulses at 1318 nm and 1540 nm. For the 1318-nm data, a Q-switched, 50-ns pulse with a spot size of 5 mm was applied to porcine skin and the damage thresholds were determined at 1 hour and 24 hours postexposure using Probit analysis. The same analysis was conducted for a Q-switched, 30-ns pulse at 1540 nm with a spot size of 5 mm. The Yucatan mini-pig was used as the skin model for human skin due to its similarity to pigmented human skin. The ED50 for these skin exposures at 24 hours postexposure was 10.5 J/cm2 for the 1318-nm exposures, and 6.1 J/cm2 for the 1540-nm exposures. These results were compared to thermal model predictions. We show that the thermal model fails to account for the ED50 values observed. A brief discussion of the possible causes of this discrepancy is presented. These thresholds are also compared with previously published skin minimum visible lesion (MVL) thresholds and with the ANSI Standard's MPE for 1318-nm lasers at 50 ns and 1540-nm lasers at 30 ns.

Paper Details

Date Published: 1 March 2006
PDF: 9 pages
Proc. SPIE 6084, Optical Interactions with Tissue and Cells XVII, 60840E (1 March 2006); doi: 10.1117/12.644757
Show Author Affiliations
Justin J. Zohner, Northrop Grumman Corp. (United States)
Kurt J. Schuster, Northrop Grumman Corp. (United States)
Lucas J. Chavey, Northrop Grumman Corp. (United States)
David J. Stolarski, Northrop Grumman Corp. (United States)
Semih S. Kumru, Air Force Research Lab. (United States)
Benjamin A. Rockwell, Air Force Research Lab. (United States)
Robert J. Thomas, Air Force Research Lab. (United States)
Clarence P. Cain, Northrop Grumman Corp. (United States)


Published in SPIE Proceedings Vol. 6084:
Optical Interactions with Tissue and Cells XVII
Steven L. Jacques; William P. Roach, Editor(s)

© SPIE. Terms of Use
Back to Top