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Proceedings Paper

Feasibility of detecting peptide phosphorylation by surface enhanced Raman scattering
Author(s): J. Moger; C.P. Winlove
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Paper Abstract

We report on the feasibility of surface enhanced Raman scattering (SERS) as a highly sensitive technique for detecting peptide phosphorylation. Compared with existing techniques for quantifying peptide phosphorylation, such as high-performance liquid chromatography (HPLC), the short scanning and processing time associated with SERS makes it an attractive alternative for measurement on a near-real-time basis at sub micro-molar concentrations. Using the recently reported drop-coating deposition Raman method we compare our SERS spectra to normal Raman spectra that would otherwise be unobtainable at such low concentration.

Paper Details

Date Published: 27 February 2006
PDF: 8 pages
Proc. SPIE 6093, Biomedical Vibrational Spectroscopy III: Advances in Research and Industry, 60930G (27 February 2006); doi: 10.1117/12.644168
Show Author Affiliations
J. Moger, Univ. of Exeter (United Kingdom)
C.P. Winlove, Univ. of Exeter (United Kingdom)

Published in SPIE Proceedings Vol. 6093:
Biomedical Vibrational Spectroscopy III: Advances in Research and Industry
Anita Mahadevan-Jansen; Wolfgang H. Petrich, Editor(s)

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