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Photodynamic action of chlorin e6 on thymocyte plasmatic and mitochondrial membrane potentials
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Paper Abstract

Transmembrane potentials appear to be cell state sensitive characteristics and can give information about cell damage initial stage. Photodynamic action of the photosensitizer chlorin e6 on plasmatic and mitochondrial membrane potentials of the rat thymus lymphocytes was studied using voltage-sensitive dye rhodamine 6G. It has been revealed that mitochondrial membrane potential is more sensitive characteristic of membrane disfunction than plasmatic one at the cell photodamage.

Paper Details

Date Published: 7 December 2006
PDF: 5 pages
Proc. SPIE 5973, Current Research on Laser Use in Oncology: 2000-2004, 59730K (7 December 2006); doi: 10.1117/12.640132
Show Author Affiliations
Grigor V. Gyulkhandanyan, Institute of Biotechnology (Armenia)
Pharmagene Co. Ltd. (Armenia)

Published in SPIE Proceedings Vol. 5973:
Current Research on Laser Use in Oncology: 2000-2004
Andrei V. Ivanov; Mishik A. Kazaryan, Editor(s)

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