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Proceedings Paper

Fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine
Author(s): I. G. Meerovich; I. Yu. Kubasova; N. A. Oborotova; G. A. Meerovich; S. A. Demura; A. Brandis; V. Rosenbach-Belkin; A. Yu. Baryshnikov; A. Scherz
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Paper Abstract

Study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochloriphyllide-serine. The peculiarities of its fluorescence excited by different lasers, dynamics and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue de-oxygenation during tumor irradiation were performed. It was shown that bacteriochloriphyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.

Paper Details

Date Published: 7 December 2006
PDF: 12 pages
Proc. SPIE 5973, Current Research on Laser Use in Oncology: 2000-2004, 59730G (7 December 2006); doi: 10.1117/12.640051
Show Author Affiliations
I. G. Meerovich, Russian Cancer Research Ctr. RAMS (Russia)
I. Yu. Kubasova, Russian Cancer Research Ctr. RAMS (Russia)
N. A. Oborotova, Russian Cancer Research Ctr. RAMS (Russia)
G. A. Meerovich, General Physics Institute RAS (Russia)
S. A. Demura, Moscow Medical Academy (Russia)
A. Brandis, Weizmann Institute of Science (Israel)
V. Rosenbach-Belkin, Weizmann Institute of Science (Israel)
A. Yu. Baryshnikov, Russian Cancer Research Ctr. RAMS (Russia)
A. Scherz, Weizmann Institute of Science (Israel)


Published in SPIE Proceedings Vol. 5973:
Current Research on Laser Use in Oncology: 2000-2004
Andrei V. Ivanov; Mishik A. Kazaryan, Editor(s)

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