Share Email Print
cover

Proceedings Paper

Adjuvant photodynamic therapy (PDT) of the superficial bladder cancer
Author(s): V. V. Sokolov; I. G. Russakov; A. A. Teplov; E. V. Filonenko; R. V. Ul'yanov; A. A. Bystrov
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Superficial transitional cell carcinoma represents 50 to 80% of newly diagnosed bladder cancer in various countries. Transurethral resection of the urinary bladder is the standard procedure for biopsy and treatment superficial bladder cancer. However recurrence tumors after transurethral resection alone is high enough (50-90%). Intravesical chemotherapy for prophylaxis after complete transurethral resection is reducing recurrence rate about 1 5%. Adjuvant intravesical Bacillus of Calmette and Guerin (BCG) is reducing recurrence rate about 30%, but frequency side effects of this therapy is very high. Purpose of this study is appreciate efficacy adjuvant PDT with photosensitizer Photogeme (Russia) of superficial bladder cancer for prophylaxis after complete transurethral resection. The follow up was from 3 to 63 months (27 months, on average). Sixty-five patients (75.6%) showed no recurrence. For the follow up period, the recurrence was revealed in 21 (24.4%) patient, in two of them it was progressing (one case of invasive growth and one case of remote metastases). Four cases of recurrence were revealed 4 months after the surgery. In other cases, the recurrence was diagnosed from 9 to 18 months.

Paper Details

Date Published: 7 December 2006
PDF: 5 pages
Proc. SPIE 5973, Current Research on Laser Use in Oncology: 2000-2004, 59730B (7 December 2006); doi: 10.1117/12.640043
Show Author Affiliations
V. V. Sokolov, P.A. Hertzen Moscow Research Oncological Institute (Russia)
I. G. Russakov, P.A. Hertzen Moscow Research Oncological Institute (Russia)
A. A. Teplov, P.A. Hertzen Moscow Research Oncological Institute (Russia)
E. V. Filonenko, P.A. Hertzen Moscow Research Oncological Institute (Russia)
R. V. Ul'yanov, P.A. Hertzen Moscow Research Oncological Institute (Russia)
A. A. Bystrov, P.A. Hertzen Moscow Research Oncological Institute (Russia)


Published in SPIE Proceedings Vol. 5973:
Current Research on Laser Use in Oncology: 2000-2004
Andrei V. Ivanov; Mishik A. Kazaryan, Editor(s)

© SPIE. Terms of Use
Back to Top