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Proceedings Paper

Double wavelength differential absorption as a technique for early diagnosis of breast cancer
Author(s): Vladimir V. Liger; Alexander V. Zybin; Kay Niemax; Yuri A. Kuritsyn; Mikhail A. Bolshov
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Paper Abstract

The double-wavelength differential molecular absorption technique with diode lasers is proposed for sensitive detection of functional status of breast tissues. The method is based on the measurement of the transmitted intensity differences of the two beams of diode lasers tuned to selected wavelengths within a broad absorption band of a human breast tissue within 700 - 800 nm spectral range. The strategy for the optimum selection of the diode laser wavelengths and initial adjustment of the detection scheme is developed. The method is demonstrated by the detection of the relative concentrations of two dyes, the optical properties of which are similar to those of a mixture of oxy- and deoxy- hemoglobin. The results of the first clinical tests of the proposed technique are briefly described.

Paper Details

Date Published: 7 December 2006
PDF: 9 pages
Proc. SPIE 5973, Current Research on Laser Use in Oncology: 2000-2004, 597304 (7 December 2006); doi: 10.1117/12.639949
Show Author Affiliations
Vladimir V. Liger, Institute of Spectroscopy, RAS (Russia)
Alexander V. Zybin, Institute of Analytical Sciences (Germany)
Kay Niemax, Institute of Analytical Sciences (Germany)
Yuri A. Kuritsyn, Institute of Spectroscopy, RAS (Russia)
Mikhail A. Bolshov, Institute of Spectroscopy, RAS (Russia)

Published in SPIE Proceedings Vol. 5973:
Current Research on Laser Use in Oncology: 2000-2004
Andrei V. Ivanov; Mishik A. Kazaryan, Editor(s)

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