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Proceedings Paper

Diagnose lung cancer by using fluorescence induce from small dose of hematoporphurin
Author(s): Jing Zhu; Jian Xu; Lin Ke; Hui-Guo Zhang
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Paper Abstract

Objective: Diagnose lung tumor clinically by using fluorescence induced from small dose of hematoporphyrin. Method : 37 patients were diagnose in which 22 patients with tumor and 15 with non-tumor disease. The patients were intravenously injected small dose of HPD (2mg/kg). The fluorescence signal was analyzed with OMA system. Results: The fluorescence signal of low dose hematoporphyrin can use to diagnose cancer. The total of 37 patients, in which 22 patients suffered tumor, the average fluorescence peak of Itumor/Inomal was 1.24±0.08. We imitated a normal distributive curve, so that most ratio of Itumor/Inomal could be included in the scope of curve. Suppose the lower limit of diagnostic criterion was 1.05. accorded to the criterion 22 is tumor. 15 of them suffered non- tumor. The average of all Itumor/Inomal was 0.98±0.06, there is significant difference between normal and cancer. 13 of 15 is non-tumor, accorded to the criterion. The positive rate was 94.6%

Paper Details

Date Published: 11 September 2006
PDF: 4 pages
Proc. SPIE 5967, 2004 Shanghai International Conference on Laser Medicine and Surgery, 59670X (11 September 2006); doi: 10.1117/12.639222
Show Author Affiliations
Jing Zhu, Renji Hospital/Shanghai Second Medical Univ. (China)
Jian Xu, Renji Hospital/Shanghai Second Medical Univ. (China)
Lin Ke, Renji Hospital/Shanghai Second Medical Univ. (China)
Hui-Guo Zhang, Renji Hospital/Shanghai Second Medical Univ. (China)


Published in SPIE Proceedings Vol. 5967:
2004 Shanghai International Conference on Laser Medicine and Surgery
Jing Zhu, Editor(s)

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