Share Email Print
cover

Proceedings Paper

Experimental study of biological effect by Nd:YAP laser (1.34μm)
Author(s): Jing Zhu; Hui-guo Zhang; Liping Lu
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Objective: To evaluate the biological effect of different power, irradiation time of Nd: YAP laser (1341nm). Method: The canine skin, bronchia, stomach, bladder, uterus were irradiated with different irradiation power and time. The effect was observed by naked eyes, light microscope, and electric microscope. Result: Having positive correlation with power and irradiating time, the biological effect of Nd: YAP laser is mainly thermal coagulation effect with some gasified ablation effect. Under the condition where the diameter of faculae irradiating on canine skin was 3 mm, the thermal coagulation dose reaching deep derma was 5W 4s, 10w 1s; the thermal coagulation dose puncturing the whole layer was 5W, 6s, 10W, 4s; the thermal coagulation dose reaching whole stratum was 10W 5s, 20W 4s, 30W 2s, 40-60W 1s on stomach (Thickness 6mm), was 40W, 2s, 30W, 3s, 20W, 4s, 10W, 6s on bladder (Thickness 6mm, irradiation underwater), was 10W, 4s on bronchia (Thickness 2 mm) and was 30W 3s, 20W 5s, 10W 6s on uterus (Thickness 6mm). Conclusion: Having positive correlation with power and irradiating time, the biological effect of Nd: YAP laser is mainly thermal coagulation effect with some gasified ablation effect. Under the condition where the diameter of faculae irradiating on canine skin was 3 mm, it is safe when the dose is 5W, and the irradiating time is less than 4s; the dose is 10W, and the irradiating time is less than 1 s. Under these conditions, the gastric area is used to coagulating and ablating. It is safe when the dose is less than 10W 5s, 20W 4s, 30W 2s. Under these condition, The bladder (thickness 6mm) is coagulated and ablated. It is safe when the dose is no more than 40W, 1s, 30W, 2s, 20W, 3s, 10W, 5s. Under the condition where bronchia (thickness 2mm) is coagulated and ablated, it is safe when the dose is less than 10W, 3s. Under the condition where uterus (thickness 6mm) is coagulated and ablated, it is safe when the dose is less than 30W, 2s, 20W, 4s, 10W, 5s.

Paper Details

Date Published: 11 September 2006
PDF: 5 pages
Proc. SPIE 5967, 2004 Shanghai International Conference on Laser Medicine and Surgery, 59670N (11 September 2006); doi: 10.1117/12.639196
Show Author Affiliations
Jing Zhu, Renji Hospital/Shanghai Second Medical Univ. (China)
Hui-guo Zhang, Renji Hospital/Shanghai Second Medical Univ. (China)
Liping Lu, Renji Hospital/Shanghai Second Medical Univ. (China)


Published in SPIE Proceedings Vol. 5967:
2004 Shanghai International Conference on Laser Medicine and Surgery
Jing Zhu, Editor(s)

© SPIE. Terms of Use
Back to Top