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Proceedings Paper

Expression of fas protein on CD4+ T cells irradiated by low level He-Ne laser in the case of psoriasis
Author(s): Fan Nie; Jing Zhu; Hui-guo Zhang
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Paper Abstract

Objective: To investigate the influence on the Expression of Fas protein on CD4+ T cells irradiated by low level He-Ne laser in the cases of psoriasis. Methods: the expression of CD4+ T Fas protein was determined in the case of psoriasis (n=5) pre and post-low level laser irradiation (30 min, 60min and 120min) by flow cytometry as compared withthe control (n=5). Results: In the cases of psoriasis, the expression of CD4+ T FAS protein 21.4±3.1% was increased significantly than that of control group 16.8±2.1% pre-irradiation, p<0.05; in the control, there is no difference between pre and post- irradiation, p>0.05; in the cases, the expression of CD4+ T Fas protein wae positively corelated to the irradiation times, when the energy density arrived to 22.92J/cm2 (60 minutes) and 45.84J/cm2 (120minutes), the expression of CD4+ T Fas protein was increased significantly as compared with pre-irradiation, p<0.05. Conclusion: The expression of CD4+ T Fas protein may be increased by low level He-Ne laser irradiation, the uncontrolled status of apoptosis could be corrected.

Paper Details

Date Published: 11 September 2006
PDF: 4 pages
Proc. SPIE 5967, 2004 Shanghai International Conference on Laser Medicine and Surgery, 59670M (11 September 2006); doi: 10.1117/12.639194
Show Author Affiliations
Fan Nie, Renji Hospital/Shanghai Second Medical Univ. (China)
Jing Zhu, Renji Hospital/Shanghai Second Medical Univ. (China)
Hui-guo Zhang, Renji Hospital/Shanghai Second Medical Univ. (China)


Published in SPIE Proceedings Vol. 5967:
2004 Shanghai International Conference on Laser Medicine and Surgery
Jing Zhu, Editor(s)

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