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Proceedings Paper

Implementing in vasion neutron capture therapy (INCT) using capillary neutron optical systems (CNOS) assessment
Author(s): G. I. Borisov; M. A. Kumakhov; R. I. Kondratenko; R. A. Spryshkova
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Paper Abstract

During LNCT the exposed object represents a practically ideal trap for neutrons In this instance, the number of neutrons that entered the object through the inlet hole is equal to the number of nuclear reactions of their absorption. Using this model and nuclear data about all considered nuclides for a biological tissue, the following INCT characteristics were theoretically calculated with regard to introduction of dosage-forming preparations based on different concentrations of lOB, l57Gd and 235U nuclides: - effective masses irradiated by thermal neutrons, - energies absorbed in the object for one thermal neutron entered, - partial content of basic dosage-forming reactions, - partial content of absorbed dosage of thermal neutrons from basic dosage-forming reactions, - quantity of thermal neutrons needed to create a total absorbed dosage of 5 Gr within the focal spot area of 0,28 cm2, - number of nuclear reactions with dosage-forming nuclides of preparations per one cell based on the cell volume of 7x7x7 m. It follows from the data obtained that dosage-forming nuclide 10B is not only the optimal but also the only one suitable for INCT. Using the obtained outcome, one can assess parameters of capillary neutron optical systems (CNOS) that are pre-requisite to implement INCT at particular experimental channels (EC) of research nuclear reactors.

Paper Details

Date Published: 6 December 2006
PDF: 6 pages
Proc. SPIE 5943, X-ray and Neutron Capillary Optics II, 59430T (6 December 2006); doi: 10.1117/12.637989
Show Author Affiliations
G. I. Borisov, Institute for Roentgen Optics (Russia)
Russian Research Ctr. Kurchatov Institute (Russia)
Unisantis SA (Switzerland)
M. A. Kumakhov, Institute for Roentgen Optics (Russia)
Russian Research Ctr. Kurchatov Institute (Russia)
Unisantis SA (Switzerland)
R. I. Kondratenko, Institute for Roentgen Optics (Russia)
Russian Research Ctr. Kurchatov Institute (Russia)
Unisantis SA (Switzerland)
R. A. Spryshkova, Cancer Research Ctr., Academy of Medical Sciences (Russia)


Published in SPIE Proceedings Vol. 5943:
X-ray and Neutron Capillary Optics II
Muradin A. Kumakhov; Richard B. Hoover, Editor(s)

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