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Proceedings Paper

Luminescent probe in the study of surfactant-induced structural changes in serum albumin in human blood plasma
Author(s): A. G. Melnikov; A. B. Pravdin; V. I. Kochubey; G. V. Melnikov
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Paper Abstract

The luminescence-kinetic technique of the monitoring of structural changes in albumins of human blood plasma that uses a luminescent probe-eosin is proposed. Phosphorescence of eosin bound to the globular proteins of blood plasma-albumins was recorded at room temperature. It is found that under the action of sodium dodecylsulfate on the albumins the rate constant of eosin phosphorescence decay grows and the intensity of eosin phosphorescence decreases. It is assumed that these changes are connected with the denaturing of blood plasma albumins by sodium dodecylsulfate.

Paper Details

Date Published: 22 June 2005
PDF: 4 pages
Proc. SPIE 5771, Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI, (22 June 2005); doi: 10.1117/12.634650
Show Author Affiliations
A. G. Melnikov, Saratov State Univ. (Russia)
A. B. Pravdin, Saratov State Univ. (Russia)
V. I. Kochubey, Saratov State Univ. (Russia)
G. V. Melnikov, Saratov State Technical Univ. (Russia)

Published in SPIE Proceedings Vol. 5771:
Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI
Valery V. Tuchin, Editor(s)

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