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Proceedings Paper

In vivo and ex vivo imaging with ultrahigh resolution full-field OCT
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Paper Abstract

Imaging of in vivo and ex vivo biological samples using full-field optical coherence tomography is demonstrated. Three variations on the original full-field optical coherence tomography instrument are presented, and evaluated in terms of performance. The instruments are based on the Linnik interferometer illuminated by a white light source. Images in the en face orientation are obtained in real-time without scanning by using a two-dimensional parallel detector array. An isotropic resolution capability better than 1 μm is achieved thanks to the use of a broad spectrum source and high numerical aperture microscope objectives. Detection sensitivity up to 90 dB is demonstrated. Image acquisition times as short as 10 μs per en face image are possible. A variety of in vivo and ex vivo imaging applications is explored, particularly in the fields of embryology, ophthalmology and botany.

Paper Details

Date Published: 7 October 2005
PDF: 6 pages
Proc. SPIE 5861, Optical Coherence Tomography and Coherence Techniques II, 586113 (7 October 2005); doi: 10.1117/12.632997
Show Author Affiliations
Kate Grieve, Ecole Superieure de Physique et de Chimie Industrielles, CNRS (France)
Gael Moneron, Ecole Superieure de Physique et de Chimie Industrielles, CNRS (France)
Wilfrid Schwartz, Ecole Superieure de Physique et de Chimie Industrielles, CNRS (France)
Albert Claude Boccara, Ecole Superieure de Physique et de Chimie Industrielles, CNRS (France)
Arnaud Dubois, Ecole Superieure de Physique et de Chimie Industrielles, CNRS (France)


Published in SPIE Proceedings Vol. 5861:
Optical Coherence Tomography and Coherence Techniques II
Wolfgang Drexler, Editor(s)

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