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Proceedings Paper

Quantifiability and image quality in noncontact fluorescence tomography
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Paper Abstract

Non-contact detection schemes for optical or fluorescence tomography offer several advantages compared to classic approaches, most importantly the ability to obtain images with a CCD in the absence of a matching fluid or fiber optics. This allows the acquisition of high density datasets, as well as simplified experimental procedures. Herein we create a unified framework for contact and non-contact detection procedures and present experimental results that show the ability of the non-contact method to quantify the concentration of fluorochromes hidden in turbid media as well as the improvement in image quality between conventional and non-contact detection.

Paper Details

Date Published: 26 October 2005
PDF: 8 pages
Proc. SPIE 5859, Photon Migration and Diffuse-Light Imaging II, 58590Z (26 October 2005); doi: 10.1117/12.632855
Show Author Affiliations
Ralf B. Schulz, German Cancer Research Ctr. (Germany)
Joerg Peter, German Cancer Research Ctr. (Germany)
Wolfhard Semmler, German Cancer Research Ctr. (Germany)
Cosimo D'Andrea, Politecnico di Milano (Italy)
Gianluca Valentini, Politecnico di Milano (Italy)
Rinaldo Cubeddu, Politecnico di Milano (Italy)

Published in SPIE Proceedings Vol. 5859:
Photon Migration and Diffuse-Light Imaging II
Kai Licha; Rinaldo Cubeddu, Editor(s)

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