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Proceedings Paper

Estimation of path length factor for measurement of haemoglobin concentration in the exposed cortical tissue
Author(s): K. Sakaguchi; T. Tachibana; K. Yokoyama; S. Furukawa; T. Katsura; A. Maki; H. Kawaguchi; E. Okada
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Paper Abstract

The change in oxy- and deoxy haemoglobin in the cortical tissue caused by brain function can be measured from multi-spectral images of exposed cortex. We cannot ignore the wavelength dependence of mean optical path length of detected light to calculate the accurate changes in concentrations of oxy- and deoxy- haemoglobin in the cortical tissue. The optical path length factor, which reflects the wavelength dependence of mean optical path length, is experimentally estimated from the multi-spectral images of exposed cortex of guinea pigs. The optical path length factor improves the accuracy in changes in concentrations of oxy- and deoxy-haemoglobin obtained from the multi-spectral images.

Paper Details

Date Published: 8 October 2005
PDF: 8 pages
Proc. SPIE 5859, Photon Migration and Diffuse-Light Imaging II, 58590S (8 October 2005); doi: 10.1117/12.632848
Show Author Affiliations
K. Sakaguchi, Keio Univ. (Japan)
T. Tachibana, Keio Univ. (Japan)
K. Yokoyama, Keio Univ. (Japan)
S. Furukawa, Keio Univ. (Japan)
T. Katsura, Hitachi Ltd. (Japan)
A. Maki, Hitachi Ltd. (Japan)
H. Kawaguchi, Hitachi Ltd. (Japan)
E. Okada, Keio Univ. (Japan)


Published in SPIE Proceedings Vol. 5859:
Photon Migration and Diffuse-Light Imaging II
Kai Licha; Rinaldo Cubeddu, Editor(s)

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