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Proceedings Paper

Structurally integrated organic light-emitting device (OLED)-based sensors for industrial and environmental security: sensors for hydrazine and anthrax
Author(s): Zhaoqun Zhou; Ruth Shinar; Bhaskar Choudhury; Louisa B. Tabatabai; Chuxiong Liao; Joseph Shinar
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Paper Abstract

The application of the new compact platform of structurally integrated, photoluminescent (bio)chemical sensors, where the photoluminescence (PL) excitation source is an OLED, to the detection of hydrazine and anthrax, is described. The hydrazine sensor is based on the reaction between nonluminescent anthracene-2,3-dicarboxaldehyde and hydrazine or hydrazine sulfate, which generates a luminescent product. The anthrax sensor is based on a Foerster resonance energy transfer (FRET) assay, where the anthrax-secreted lethal factor enzyme cleaves certain labeled peptides at a specific site. The cleaving separates the FRET donor-acceptor pair, resulting in an increase in the PL of the donor, which was previously absorbed by the acceptor.

Paper Details

Date Published: 8 November 2005
PDF: 9 pages
Proc. SPIE 5994, Chemical and Biological Sensors for Industrial and Environmental Security, 59940E (8 November 2005); doi: 10.1117/12.631426
Show Author Affiliations
Zhaoqun Zhou, Iowa State Univ. (United States)
Ruth Shinar, Iowa State Univ. (United States)
Bhaskar Choudhury, Iowa State Univ. (United States)
Louisa B. Tabatabai, Iowa State Univ. (United States)
National Animal Disease Ctr. (United States)
Chuxiong Liao, Iowa State Univ. (United States)
Joseph Shinar, Iowa State Univ. (United States)

Published in SPIE Proceedings Vol. 5994:
Chemical and Biological Sensors for Industrial and Environmental Security
Arthur J. Sedlacek; Steven D. Christesen; Roger J. Combs; Tuan Vo-Dinh, Editor(s)

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