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Proceedings Paper

Nanosensing applications of In2O3 nanowires and carbon nanotubes
Author(s): Chongwu Zhou; Chao Li; Marco Curreli; Henry Lin; Fumiaki N. Ishikawa; Ram Datar; Richard J. Cote; Mark E. Thompson
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Paper Abstract

We report complementary detection of prostate-specific antigen (PSA) using n-type In2O3 nanowires and p-type carbon nanotubes. Our innovation involves developing an approach to covalently attach antibodies to In2O3 NW surfaces via the onsite surface synthesis of phosphoric acid-succinylimide ester. Electronic measurements under dry conditions revealed complementary response for In2O3 NW and SWNT devices after the binding of PSA. Real time detection in solution has also been demonstrated for PSA down to 5 ng/mL, a benchmark concentration significant for clinical diagnosis of prostate cancer, which is the most frequently diagnosed cancer.

Paper Details

Date Published: 17 November 2005
PDF: 4 pages
Proc. SPIE 6008, Nanosensing: Materials and Devices II, 60080F (17 November 2005); doi: 10.1117/12.631077
Show Author Affiliations
Chongwu Zhou, Univ. of Southern California, Los Angeles (United States)
Chao Li, Univ. of Southern California, Los Angeles (United States)
Marco Curreli, Univ. of Southern California, Los Angeles (United States)
Henry Lin, Univ. of Southern California, Los Angeles (United States)
Fumiaki N. Ishikawa, Univ. of Southern California, Los Angeles (United States)
Ram Datar, Univ. of Southern California, Los Angeles (United States)
Richard J. Cote, Univ. of Southern California, Los Angeles (United States)
Mark E. Thompson, Univ. of Southern California, Los Angeles (United States)


Published in SPIE Proceedings Vol. 6008:
Nanosensing: Materials and Devices II
M. Saif Islam; Achyut K. Dutta, Editor(s)

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