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Proceedings Paper

Preliminary results: exploring the interactions of quantum dots with whole blood components
Author(s): Hans C. Fischer; Eliseo Papa; Lichuan Liu; K. Sandy Pang; Warren C. W. Chan
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Paper Abstract

Biocompatible ZnS capped CdSe fluorescent semiconductor nanocrystals (quantum dots, QDs) exhibit great potential as imaging agents with biomedical and clinical relevance. However, little is known about the fate of the quantum dots in vivo, and the importance of chemical and physical composition that may influence their behavior in vivo. When the QDs are introduced in vivo, the first interactions with blood components will dictate their kinetic behavior in vivo. We present some preliminary results that demonstrate the interactions of the quantum dots with plasma proteins and that quantum dots can be trapped in fibrous networks.

Paper Details

Date Published: 12 October 2005
PDF: 6 pages
Proc. SPIE 5969, Photonic Applications in Biosensing and Imaging, 59690E (12 October 2005); doi: 10.1117/12.629344
Show Author Affiliations
Hans C. Fischer, Univ. of Toronto (Canada)
Eliseo Papa, Univ. of Toronto (Canada)
Lichuan Liu, Univ. of Toronto (Canada)
K. Sandy Pang, Univ. of Toronto (Canada)
Warren C. W. Chan, Univ. of Toronto (Canada)

Published in SPIE Proceedings Vol. 5969:
Photonic Applications in Biosensing and Imaging
Brian C. Wilson; Richard I. Hornsey; Warren C. W. Chan; Ulrich J. Krull; Robert A. Weersink; Kui Yu, Editor(s)

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