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Proceedings Paper

Strain measurement of a mouse bone by 3D-electronic speckle pattern interferometry (3D-ESPI)
Author(s): Praveen R. Samala; Min Su; Sheng Liu; Hui H. Jiang; Hiroki Yokota; Lianxiang Yang
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Paper Abstract

Bone is a mechanosensitive tissue that adapts its mass, architecture and mechanical properties to mechanical loading. Appropriate mechanical loads provide an effective means to stimulate bone remodeling and prevent from bone loss. It is controversial whether in situ strain in bone is a critical determinant in enhancement of bone formation, and it is therefore important to evaluate load-driven strain in bone. Using electronic speckle pattern interferometry, we determined high-resolution three-dimensional strains on the mouse femur in response to two loading modalities: an axial loading modality (ALM) and a knee loading modality (KLM). We demonstrated that these two loading modalities induced a different pattern of strain distributions. ALM generated strain in the midshaft of cortical bone, while strains with KLM were concentrated on the distal epiphysis of the mouse femur. Since KLM is capable of enhancing bone formation in cortical bone distant from the knee, the current results indicate that in situ strain is not always necessary for load-driven bone formation.

Paper Details

Date Published: 18 August 2005
PDF: 9 pages
Proc. SPIE 5880, Optical Diagnostics, 58800C (18 August 2005); doi: 10.1117/12.617670
Show Author Affiliations
Praveen R. Samala, Oakland Univ. (United States)
Min Su, Indiana Univ./Purdue Univ. Indianapolis (United States)
Sheng Liu, Oakland Univ. (United States)
Hui H. Jiang, Indiana Univ./Purdue Univ. Indianapolis (United States)
Hiroki Yokota, Indiana Univ./Purdue Univ. Indianapolis (United States)
Lianxiang Yang, Oakland Univ. (United States)


Published in SPIE Proceedings Vol. 5880:
Optical Diagnostics
Leonard M. Hanssen; Patrick V. Farrell, Editor(s)

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