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Proceedings Paper

Advanced multifocus confocal laser scanning microscope for single molecule studies
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Paper Abstract

A new multi-focus multi-confocal set-up for performing fluorescence spectroscopy of single molecules in solution is presented. The ultimate goal of the set-up is to track individual molecules during diffusion in solution, when all standard methods of trapping such as optical tweezers or dielectrophoretic traps fail. We present here a detailed description of the experimental setup and show first experimental results.

Paper Details

Date Published: 29 March 2005
PDF: 8 pages
Proc. SPIE 5699, Imaging, Manipulation, and Analysis of Biomolecules and Cells: Fundamentals and Applications III, (29 March 2005); doi: 10.1117/12.611147
Show Author Affiliations
Thomas Dertinger, Forschungszentrum Juelich (Germany)
Felix Koberling, PicoQuant GmbH (Germany)
Ales Benda, J. Heyrovsky Institute of Physical Chemistry (Czech Republic)
Rainer Erdmann, PicoQuant GmbH (Germany)
Martin Hof, J. Heyrovsky Institute of Physical Chemistry (Czech Republic)
Joerg Enderlein, Forschungszentrum Juelich (Germany)


Published in SPIE Proceedings Vol. 5699:
Imaging, Manipulation, and Analysis of Biomolecules and Cells: Fundamentals and Applications III
Dan V. Nicolau; Dan V. Nicolau; Jörg Enderlein; Ramesh Raghavachari; Robert C. Leif; Daniel L. Farkas, Editor(s)

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