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Proceedings Paper

Porous-silicon-based oligonucleotide chips
Author(s): Li Shao; Shaoqiang Chen; Jian Zhang; Jianzhong Zhu; Ziqiang Zhu; Bin Zhu
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Paper Abstract

A novel oligonucleotide chip with porous silicon / oxidized porous silicon (PS/OPS) as its substrate has been developed. The attachment rate and detection sensitivity were improved obviously due to enormous surface area of PS/OPS compared to the existing conventional techniques. No dependence of storage condition on the detection sensitivity is found (signals variation is within SD). Stability of the oligonucleotide chips is good.

Paper Details

Date Published: 8 December 2004
PDF: 4 pages
Proc. SPIE 5774, Fifth International Conference on Thin Film Physics and Applications, (8 December 2004); doi: 10.1117/12.607477
Show Author Affiliations
Li Shao, East China Normal Univ. (China)
Shaoqiang Chen, East China Normal Univ. (China)
Jian Zhang, East China Normal Univ. (China)
Jianzhong Zhu, East China Normal Univ. (China)
Ziqiang Zhu, East China Normal Univ. (China)
Bin Zhu, East China Normal Univ. (China)

Published in SPIE Proceedings Vol. 5774:
Fifth International Conference on Thin Film Physics and Applications
Junhao Chu; Zongsheng Lai; Lianwei Wang; Shaohui Xu, Editor(s)

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