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Proceedings Paper

Development of a PCR free, fieldable, rapid, accurate, and sensitive bio-electronic DNA biosensor
Author(s): Doyle Hill; David Chafin; Roberta Greco; Samina Jafri; Richard Murante; John Noonan; An Pham; Scott Seabridge; Vera Tannous; Karl VanDerMeid; Daguang Wang; Nate Wescott; Kristin McFarlane; Sanjiv Shah
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Paper Abstract

The objective of this study was to demonstrate proof of concept for the Integrated Nano-Technologies BioDetect Bacillus anthracis electronic DNA sensor. B. anthracis Ames strain DNA was successfully detected by the formation of DNA bridges on the sensor. The bridges were coated with metal, resulting in a significant drop in electrical resistance. In this small test, at a relatively high DNA concentration, the overall accuracy of the sensor was 90.7%. The technology shows significant promise for future development as a bio-agent detection system.

Paper Details

Date Published: 20 May 2005
PDF: 10 pages
Proc. SPIE 5778, Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Security and Homeland Defense IV, (20 May 2005); doi: 10.1117/12.606722
Show Author Affiliations
Doyle Hill, Integrated Nano-Technologies (United States)
David Chafin, Integrated Nano-Technologies (United States)
Roberta Greco, Integrated Nano-Technologies (United States)
Samina Jafri, Integrated Nano-Technologies (United States)
Richard Murante, Integrated Nano-Technologies (United States)
John Noonan, Integrated Nano-Technologies (United States)
An Pham, Integrated Nano-Technologies (United States)
Scott Seabridge, Integrated Nano-Technologies (United States)
Vera Tannous, Integrated Nano-Technologies (United States)
Karl VanDerMeid, Integrated Nano-Technologies (United States)
Daguang Wang, Integrated Nano-Technologies (United States)
Nate Wescott, Integrated Nano-Technologies (United States)
Kristin McFarlane, U.S. Army Edgewood Chemical Biological Ctr. (United States)
Sanjiv Shah, U.S. Army Edgewood Chemical Biological Ctr. (United States)


Published in SPIE Proceedings Vol. 5778:
Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Security and Homeland Defense IV
Edward M. Carapezza, Editor(s)

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